Ok, after much procrastination, i have finally re-designed http://Ionisis.com

I wanted to keep a 'dark-technology' feel to it, and be much 'different' from the norm, while still remaining clean, clear, attractive, and easy to navigate.

standard tips and tweaks

http://websiteoptimization.com/services/analyze/ speed tweaks: pretty good, but

This site is not using HTTP compression, otherwise called content encoding using gzip. Consider compressing your textual content (XHTML, JavaScript, etc.) with mod_gzip or similar products

Text,,, html, php, css, js, respond well to mod_gzip, or, strip out comments and whitespace from production code, great for debugging, lousy for transmission times.

http://validator.w3.org/ HTML Pass
http://jigsaw.w3.org/css-validator/ CSS Pass
http://demo.opera-mini.net/demo.html?ionisis.com/ Handheld, ::blankscreen::

: ceo cfo carry blackberry or have the latest greatest hidef flatscreen widescreen desktop, the site has to work in both, doesnt have to be identical, but has to work

http://www.browsershots.org Other Browsers (didnt check, takes half an hour to post back all the possible combinations, Im lazy)

Consider Hosting your own video, NOT professional to have branded youtube in your main page.