As a personal taste, I always use CSS to do all of my site design if I can help it. It just makes things flexible in the end. You can put all body content inside a <div> and set width to a relative or absolute size. For example, setting <div style="width:720px"> sets a fixed width that would look fine at 800x600, and leave extra space at higher resolutions (as is here on DaniWeb).

You could also set width:80% which would set a variable width based on the user's current browser window. It would occupy 80% of their browser window, for example. If the surfer were to resize their browser window, the size would resize consistantly.

I'm not exactly sure if this is what you're asking.