No difference - it should always, and I mean always, be well coded, and in almost all circumstances, accessible.

I have seen so many sites with damned clever bits.... and but for ignorance or laziness, it fails to be highly usable and not the slightest accessible.

I admit, I'm not perfect, took a while before I thought of making form elemnts measued in EM for height etc... but so many people claim to be web-site-develoeprs/designers/builders... and have not got a clue.

Still, at least there are some who are willing to learn and improve - such as people on forums such as this!
(Thank god for communities )