You will need to turn these off via Services as they load via Services during Start up.
To do this do the following;
Go to Start, Control Panel, Administrative Tools, Services. When Services opens then scroll down to the following entry;
PC Tools Security Service (sdCoreService) - PC Tools - C:\Program Files\Spyware Doctor\pctsSvc.exe.
Double click that entry. A box will open. Look on that box first at Service Status. If it show it as Started then click the Stop button to turn it off.
Then go up to the middle of that same box and you will see Start Up Type. Change that to Disabled.