Also here are my computer specs:
AMD Athlon X2 Dual Core Processor 4400+, 2.2 GHz
2 GB RAM
512 MB ATI Radeon HD 4800

ok,start with this clean up tool ,easy to use , www.ccleaner.com
a little how to use it here .
http://download.cnet.com/8301-2007_4-9855787-12.html

when using the registry cleaning part make sure to say yes to backup registry the first time ,also make sure to scan it 2-4 time or until it finds no more problems

How much space is left on C:?
Run chkdsk /R on both drives.

Hey again,

I ended up formatting my C:\ yesterday and I began to reinstall some programs I lost like Mozilla and graphics card drivers, etc. The computer was running normal again but now today it is doing the same thing again. I ran another virus scan and found nothing and I ran CCleaner and fixed everything and there's still a problem... I really do not want to have to format my other hard drive. There's a lot of stuff on there that I'd have to backup. Any other ideas as to what I can do. Thanks again.

scan with hijackthis and post the log ,
also ,what size cpu and how much ram do you have

AMD Athlon X2 Dual Core Processor 4400+, 2.2 GHz
2 GB RAM

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 2:36:51 PM, on 3/18/2009
Platform: Windows XP SP3 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 (6.00.2900.5512)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
C:\Program Files\Alwil Software\Avast4\ashServ.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\ATI Technologies\ATI.ACE\Core-Static\MOM.exe
C:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\ATI Technologies\ATI.ACE\Core-Static\ccc.exe
C:\WINDOWS\system32\devldr32.exe
C:\Program Files\Mozilla Firefox\firefox.exe
C:\Program Files\Alwil Software\Avast4\ashMaiSv.exe
C:\Program Files\Alwil Software\Avast4\ashWebSv.exe
C:\Program Files\Alwil Software\Avast4\ashSimpl.exe
C:\WINDOWS\system32\wuauclt.exe
C:\Program Files\Malwarebytes' Anti-Malware\mbam.exe
C:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\mscorsvw.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
O2 - BHO: AcroIEHelperStub - {18DF081C-E8AD-4283-A596-FA578C2EBDC3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelperShim.dll
O2 - BHO: Groove GFS Browser Helper - {72853161-30C5-4D22-B7F9-0BBC1D38A37E} - C:\PROGRA~1\MI1933~1\Office12\GRA8E1~1.DLL
O2 - BHO: Java(tm) Plug-In 2 SSV Helper - {DBC80044-A445-435b-BC74-9C25C1C588A9} - C:\Program Files\Java\jre6\bin\jp2ssv.dll
O2 - BHO: JQSIEStartDetectorImpl - {E7E6F031-17CE-4C07-BC86-EABFE594F69C} - C:\Program Files\Java\jre6\lib\deploy\jqs\ie\jqs_plugin.dll
O4 - HKLM\..\Run: [StartCCC] "C:\Program Files\ATI Technologies\ATI.ACE\Core-Static\CLIStart.exe" MSRun
O4 - HKLM\..\Run: [avast!] C:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
O4 - HKLM\..\Run: [MSConfig] C:\WINDOWS\PCHealth\HelpCtr\Binaries\MSConfig.exe /auto
O4 - HKLM\..\RunOnce: [Malwarebytes' Anti-Malware] C:\Program Files\Malwarebytes' Anti-Malware\mbamgui.exe /install /silent
O4 - HKLM\..\RunOnce: [NoIE4StubProcessing] C:\WINDOWS\system32\reg.exe DELETE "HKLM\SOFTWARE\Microsoft\Active Setup\Installed Components" /v "NoIE4StubProcessing" /f
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MI1933~1\Office12\EXCEL.EXE/3000
O9 - Extra button: Send to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MI1933~1\Office12\ONBttnIE.dll
O9 - Extra 'Tools' menuitem: S&end to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MI1933~1\Office12\ONBttnIE.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MI1933~1\Office12\REFIEBAR.DLL
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O16 - DPF: {17492023-C23A-453E-A040-C7C580BBF700} (Windows Genuine Advantage Validation Tool) - http://go.microsoft.com/fwlink/?linkid=39204
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://update.microsoft.com/windowsu...?1237334682953
O18 - Protocol: grooveLocalGWS - {88FED34C-F0CA-4636-A375-3CB6248B04CD} - C:\PROGRA~1\MI1933~1\Office12\GR99D3~1.DLL
O23 - Service: avast! iAVS4 Control Service (aswUpdSv) - ALWIL Software - C:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
O23 - Service: Ati HotKey Poller - ATI Technologies Inc. - C:\WINDOWS\system32\Ati2evxx.exe
O23 - Service: ATI Smart - Unknown owner - C:\WINDOWS\system32\ati2sgag.exe
O23 - Service: avast! Antivirus - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashServ.exe
O23 - Service: avast! Mail Scanner - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashMaiSv.exe
O23 - Service: avast! Web Scanner - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashWebSv.exe

--
End of file - 4846 bytes

I am currently running another virus scan and malware scan again too so once those finish, I'll post the results. Thanks.

i would uninstall this program ,
O2 - BHO: Groove GFS Browser Helper

and this is noteworth .othere forum said it registry need for IE install blocked by tea timer .
O4 - HKLM\..\RunOnce: [NoIE4StubProcessing] C:\WINDOWS\system32\reg.exe DELETE "HKLM\SOFTWARE\Microsoft\Active Setup\Installed Components" /v "NoIE4StubProcessing" /f

im leaving forum for a [3or4]few hrs ,