Sockets can be a bit challenging of a concept at first, mostly because in order to make an asynchonous connection, a certain degree of multi-threading must be used. The socket class will handle the creation of the thread, but you must learn how to invoke it, and when. This will require some knowledge of delegates, as these must be used to invoke a function in the main thread from the socket threads. The client will be pretty straight forward, but the server requires a bit more attention, since it is the one that must establish the TCP connections. If you are comfortable with the above concepts, then no problem! If you aren't then feel free to ask some questions.

The easiest way to provide communication between systems - programs is a Web Service.