Hi I'm having a problem where when I open up My Computer I try to acess my documents and it opens for a moment then I get the pop up error message, sometimes the screen doesn't even load it just has the flashlight looking for the file. When I try loading My Computer from the start menu explorer locks up

The error I get lists this-
C:\DOCUME~1\Dafatman\LOCALS~1\Temp\e75_appcompat.txt

rarely another error message comes up about Dr. Watson post-mortem error log or something of the like.

-here is the hijack this log
Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 5:49:19 PM, on 9/4/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Bonjour\mDNSResponder.exe
C:\WINDOWS\eHome\ehRecvr.exe
C:\WINDOWS\eHome\ehSched.exe
C:\WINDOWS\system32\svchost.exe
c:\program files\mcafee.com\agent\mcdetect.exe
c:\PROGRA~1\mcafee.com\vso\mcshield.exe
c:\PROGRA~1\mcafee.com\agent\mctskshd.exe
C:\PROGRA~1\McAfee.com\PERSON~1\MpfService.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\nvsvc32.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\UAService7.exe
C:\WINDOWS\system32\dllhost.exe
C:\PROGRA~1\mcafee.com\agent\mcagent.exe
C:\PROGRA~1\McAfee\SPAMKI~1\MskAgent.exe
C:\Program Files\Messenger\msmsgs.exe
C:\WINDOWS\system32\wuauclt.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Program Files\HP\Smart Web Printing\hpswp_clipbook.exe
C:\WINDOWS\explorer.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Local Page =
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Local Page =
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
O2 - BHO: HP Print Enhancer - {0347C33E-8762-4905-BF09-768834316C61} - C:\Program Files\HP\Smart Web Printing\hpswp_printenhancer.dll
O2 - BHO: HP Print Clips - {053F9267-DC04-4294-A72C-58F732D338C0} - C:\Program Files\HP\Smart Web Printing\hpswp_framework.dll
O2 - BHO: McBrwHelper Class - {227B8AA8-DAF2-4892-BD1D-73F568BCB24E} - c:\program files\mcafee.com\mps\mcbrhlpr.dll
O2 - BHO: McAfee PopupKiller - {3EC8255F-E043-4cae-8B3B-B191550C2A22} - c:\program files\mcafee.com\mps\popupkiller.dll
O2 - BHO: McAfee Anti-Phishing Filter - {41D68ED8-4CFF-4115-88A6-6EBB8AF19000} - c:\program files\mcafee\spamkiller\mcapfbho.dll
O3 - Toolbar: McAfee VirusScan - {BA52B914-B692-46c4-B683-905236F6F655} - c:\progra~1\mcafee.com\vso\mcvsshl.dll
O4 - HKLM\..\Run: [MCAgentExe] c:\PROGRA~1\mcafee.com\agent\mcagent.exe
O4 - HKLM\..\Run: [MSKAGENTEXE] C:\PROGRA~1\McAfee\SPAMKI~1\MskAgent.exe
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\system32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [MCUpdateExe] C:\PROGRA~1\mcafee.com\agent\mcupdate.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKCU\..\Run: [MSMSGS] "C:\Program Files\Messenger\msmsgs.exe" /background
O9 - Extra button: HP Clipbook - {58ECB495-38F0-49cb-A538-10282ABF65E7} - C:\Program Files\HP\Smart Web Printing\hpswp_extensions.dll
O9 - Extra button: HP Smart Select - {700259D7-1666-479a-93B1-3250410481E8} - C:\Program Files\HP\Smart Web Printing\hpswp_extensions.dll
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O23 - Service: Apple Mobile Device - Apple, Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\1050\Intel 32\IDriverT.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: McAfee WSC Integration (McDetect.exe) - McAfee, Inc - c:\program files\mcafee.com\agent\mcdetect.exe
O23 - Service: McAfee.com McShield (McShield) - McAfee Inc. - c:\PROGRA~1\mcafee.com\vso\mcshield.exe
O23 - Service: McAfee Task Scheduler (McTskshd.exe) - McAfee, Inc - c:\PROGRA~1\mcafee.com\agent\mctskshd.exe
O23 - Service: McAfee SecurityCenter Update Manager (mcupdmgr.exe) - McAfee, Inc - C:\PROGRA~1\McAfee.com\Agent\mcupdmgr.exe
O23 - Service: McAfee Personal Firewall Service (MpfService) - McAfee Corporation - C:\PROGRA~1\McAfee.com\PERSON~1\MpfService.exe
O23 - Service: McAfee SpamKiller Server (MskService) - McAfee Inc. - C:\PROGRA~1\McAfee\SPAMKI~1\MSKSrvr.exe
O23 - Service: NVIDIA Display Driver Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\system32\nvsvc32.exe
O23 - Service: SecuROM User Access Service (V7) (UserAccess7) - Unknown owner - C:\WINDOWS\system32\UAService7.exe

--
End of file - 4802 bytes

Any help would be greatly appreciated

more to add

it seems any time I open a folder or anything that is based in or around explorer itself I get the error

-Hope this helps

Dafat... this is probably not malware related [your log shows as clean, by the way], more an error in the way explorer limks to the various files and folders. What happens when you paste this into the Run box:
C:\DOCUME~1\Dafatman\LOCALS~1\Temp
-normal behaviour is for an explorer window to open to that folder. If it does, rename that file, e75_appcompat.txt to e75_appcompat.txt.bak

I've been having a simular problem only i get this pop up:

C:\DOCUME~1\Sam\LOCALS~1\Temp\WER22.tmp.dir00\appcompat.txt

Windows Error Reporting... like do you want to send this error report to M$?.. and that is the file that will be sent. You can turn error reporting off, you know.... but the msg is just the symptom of a problem you have with your software or the machine...