My computer's been running really slow. So i ran Spybot Search & Destroy, Maleware's Anti-Maleware, and all the other recommended stuff and they found nothing. Heres a the hijack this logfile

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 6:50:21 PM, on 10/16/2008
Platform: Windows XP SP3 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16735)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\hkcmd.exe
C:\Program Files\Defender Pro\Defender Pro Internet Security 6.0\avp.exe
C:\Program Files\Java\jre1.6.0_07\bin\jusched.exe
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\Program Files\Yahoo!\Search Protection\SearchProtection.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
C:\Program Files\Common Files\Microsoft Shared\VS7DEBUG\MDM.EXE
C:\Program Files\Yahoo!\Messenger\ymsgr_tray.exe
C:\Program Files\Defender Pro\Defender Pro Internet Security 6.0\avz.exe
C:\Program Files\Defender Pro\Defender Pro Internet Security 6.0\avz.exe
C:\Program Files\Internet Explorer\iexplore.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.yahoo.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.yahoo.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://us.rd.yahoo.com/customize/ie/.../www.yahoo.com
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = http://us.rd.yahoo.com/customize/ie/...ch/search.html
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://us.rd.yahoo.com/customize/ie/.../www.yahoo.com
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.yahoo.com/
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = http://us.rd.yahoo.com/customize/ie/.../www.yahoo.com
R3 - URLSearchHook: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\Program Files\Yahoo!\Companion\Installs\cpn1\yt.dll
O2 - BHO: &Yahoo! Toolbar Helper - {02478D38-C3F9-4efb-9B51-7695ECA05670} - C:\Program Files\Yahoo!\Companion\Installs\cpn1\yt.dll
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: Yahoo! IE Services Button - {5BAB4B5B-68BC-4B02-94D6-2FC0DE4A7897} - C:\Program Files\Yahoo!\Common\yiesrvc.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_07\bin\ssv.dll
O2 - BHO: SingleInstance Class - {FDAD4DA1-61A2-4FD8-9C17-86F7AC245081} - C:\Program Files\Yahoo!\Companion\Installs\cpn1\YTSingleInstance.dll
O3 - Toolbar: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\Program Files\Yahoo!\Companion\Installs\cpn1\yt.dll
O4 - HKLM\..\Run: [IgfxTray] C:\WINDOWS\system32\igfxtray.exe
O4 - HKLM\..\Run: [HotKeysCmds] C:\WINDOWS\system32\hkcmd.exe
O4 - HKLM\..\Run: [Adobe Reader Speed Launcher] "C:\Program Files\Adobe\Reader 8.0\Reader\Reader_sl.exe"
O4 - HKLM\..\Run: [AVP] "C:\Program Files\Defender Pro\Defender Pro Internet Security 6.0\avp.exe"
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre1.6.0_07\bin\jusched.exe"
O4 - HKLM\..\Run: [TrojanScanner] C:\Program Files\Trojan Remover\Trjscan.exe
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
O4 - HKLM\..\Run: [YSearchProtection] "C:\Program Files\Yahoo!\Search Protection\SearchProtection.exe"
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [Performance Center] C:\Program Files\Ascentive\Performance Center\APCMain.exe -m
O4 - HKCU\..\Run: [Yahoo! Pager] "C:\Program Files\Yahoo!\Messenger\YahooMessenger.exe" -quiet
O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
O4 - HKCU\..\Run: [Search Protection] C:\Program Files\Yahoo!\Search Protection\SearchProtection.exe
O4 - HKCU\..\Run: [YSearchProtection] C:\Program Files\Yahoo!\Search Protection\SearchProtection.exe
O8 - Extra context menu item: Add to Anti-Banner - C:\Program Files\Defender Pro\Defender Pro Internet Security 6.0\ie_banner_deny.htm
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~3\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_07\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_07\bin\ssv.dll
O9 - Extra button: Web Anti-Virus statistics - {1F460357-8A94-4D71-9CA3-AA4ACF32ED8E} - C:\Program Files\Defender Pro\Defender Pro Internet Security 6.0\scieplugin.dll
O9 - Extra button: Yahoo! Services - {5BAB4B5B-68BC-4B02-94D6-2FC0DE4A7897} - C:\Program Files\Yahoo!\Common\yiesrvc.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~3\OFFICE11\REFIEBAR.DLL
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O16 - DPF: {30528230-99f7-4bb4-88d8-fa1d4f56a2ab} (Installation Support) - C:\Program Files\Yahoo!\Common\Yinsthelper.dll
O16 - DPF: {48DD0448-9209-4F81-9F6D-D83562940134} - http://lads.myspace.com/upload/MySpaceUploader1006.cab
O16 - DPF: {56762DEC-6B0D-4AB4-A8AD-989993B5D08B} (OnlineScanner Control) - http://www.eset.eu/buxus/docs/OnlineScanner.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://www.update.microsoft.com/wind...?1199317215331
O16 - DPF: {6E32070A-766D-4EE6-879C-DC1FA91D2FC3} (MUWebControl Class) - http://www.update.microsoft.com/micr...?1199317384613
O16 - DPF: {B516CA4E-A5BA-405C-AFCF-A97F08CC7429} - http://www.shockwave.com/content/bur...sPlayer_v4.cab
O16 - DPF: {C02226EB-A5D7-4B1F-BD7E-635E46C2288D} (Toontown Installer ActiveX Control) - http://a.download.toontown.com/sv1.0.35.16/ttinst.cab
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://fpdownload2.macromedia.com/ge...sh/swflash.cab
O20 - AppInit_DLLs: C:\PROGRA~1\DEFEND~1\DEFEND~1.0\adialhk.dll
O23 - Service: Defender Pro Internet Security (AVP) - Defender Pro - C:\Program Files\Defender Pro\Defender Pro Internet Security 6.0\avz.exe

--
End of file - 7051 bytes


Anything?

Nothing there that I can see. Have you tried clearing out all your temp files and giving it a defrag?

yea i've done both, i'm not sure whats up with it..

Try an online virus scan and see what comes up. Might be a HD dying?