I have a problem with a worm that has infested my registry. It keeps closing my explorer causing my desktop icons to go away and come back. I just ran Hijack this and this is what I got. Any help please I do not know where to go from here!

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 11:41:36 PM, on 1/22/2009
Platform: Windows XP SP3 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16762)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\AntiVir PersonalEdition Classic\avguard.exe
C:\Program Files\ANI\ANIWZCS2 Service\ANIWZCSdS.exe
C:\Program Files\AntiVir PersonalEdition Classic\sched.exe
C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Memeo\AutoBackup\MemeoService.exe
C:\Program Files\Java\jre6\bin\jqs.exe
C:\WINDOWS\system32\lxddcoms.exe
C:\Program Files\Nero\Nero8\Nero BackItUp\NBService.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\Program Files\Viewpoint\Common\ViewpointService.exe
C:\WINDOWS\system32\ZoneLabs\vsmon.exe
C:\Program Files\Viewpoint\Viewpoint Manager\ViewMgr.exe
C:\WINDOWS\system32\taskmgr.exe
C:\Program Files\Mozilla Firefox\firefox.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.yahoo.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = http://us.rd.yahoo.com/customize/ie/...ch/search.html
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Local Page =
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Local Page =
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
O3 - Toolbar: &Google - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - c:\program files\google\googletoolbar3.dll
O3 - Toolbar: NetXfer - {C16CBAAC-A75C-4DB5-A0DD-CDF5CAFCDD3A} - C:\Program Files\Xi\NetXfer\NXToolBar.dll
O4 - HKLM\..\Run: [avgnt] "C:\Program Files\AntiVir PersonalEdition Classic\avgnt.exe" /min
O4 - HKLM\..\Run: [D-Link AirPlus XtremeG DWL-G520] C:\Program Files\D-Link\AirPlus XtremeG DWL-G520\AirPlusCFG.exe
O4 - HKLM\..\Run: [ANIWZCS2Service] C:\Program Files\ANI\ANIWZCS2 Service\WZCSLDR2.exe
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\system32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [NvMediaCenter] RUNDLL32.EXE C:\WINDOWS\system32\NvMcTray.dll,NvTaskbarInit
O4 - HKLM\..\Run: [KernelFaultCheck] %systemroot%\system32\dumprep 0 -k
O4 - HKLM\..\Run: [SmartGuardian] C:\Program Files\ITE\Smart Guardian\ITESmart.exe
O4 - HKLM\..\Run: [amd_dc_opt] C:\Program Files\AMD\Dual-Core Optimizer\amd_dc_opt.exe
O4 - HKLM\..\Run: [CTHelper] CTHELPER.EXE
O4 - HKLM\..\Run: [ZoneAlarm Client] "C:\Program Files\Zone Labs\ZoneAlarm\zlclient.exe"
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre6\bin\jusched.exe"
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [swg] C:\Program Files\Google\GoogleToolbarNotifier\GoogleToolbarNotifier.exe
O8 - Extra context menu item: &Yahoo! Search - file:///C:\Program Files\Yahoo!\Common/ycsrch.htm
O8 - Extra context menu item: Download all by NetXfer - C:\Program Files\Xi\NetXfer\NXAddList.html
O8 - Extra context menu item: Download by NetXfer - C:\Program Files\Xi\NetXfer\NXAddLink.html
O8 - Extra context menu item: Send To &Bluetooth - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie_ctx.htm
O8 - Extra context menu item: Yahoo! &Dictionary - file:///C:\Program Files\Yahoo!\Common/ycdict.htm
O8 - Extra context menu item: Yahoo! &Maps - file:///C:\Program Files\Yahoo!\Common/ycmap.htm
O8 - Extra context menu item: Yahoo! &SMS - file:///C:\Program Files\Yahoo!\Common/ycsms.htm
O9 - Extra button: Yahoo! Services - {5BAB4B5B-68BC-4B02-94D6-2FC0DE4A7897} - C:\Program Files\Yahoo!\Common\yiesrvc.dll
O9 - Extra button: Bonjour - {7F9DB11C-E358-4ca6-A83D-ACC663939424} - C:\Program Files\Bonjour\ExplorerPlugin.dll
O9 - Extra button: AIM - {AC9E2541-2814-11d5-BC6D-00B0D0A1DE45} - C:\Program Files\AIM\aim.exe
O9 - Extra button: PartyPoker.com - {B7FE5D70-9AA2-40F1-9C6B-12A255F085E1} - C:\Program Files\PartyPoker\PartyPoker.exe (file missing)
O9 - Extra 'Tools' menuitem: PartyPoker.com - {B7FE5D70-9AA2-40F1-9C6B-12A255F085E1} - C:\Program Files\PartyPoker\PartyPoker.exe (file missing)
O9 - Extra button: @btrez.dll,-4015 - {CCA281CA-C863-46ef-9331-5C8D4460577F} - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
O9 - Extra 'Tools' menuitem: @btrez.dll,-4017 - {CCA281CA-C863-46ef-9331-5C8D4460577F} - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie.htm
O9 - Extra button: Run IMVU - {d9288080-1baa-4bc4-9cf8-a92d743db949} - C:\Documents and Settings\Justin\Start Menu\Programs\IMVU\Run IMVU.lnk (file missing)
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O15 - Trusted Zone: *.line6.net
O16 - DPF: {0A5FD7C5-A45C-49FC-ADB5-9952547D5715} (Creative Software AutoUpdate) - http://www.creative.com/su/ocx/15030/CTSUEng.cab
O16 - DPF: {2917297F-F02B-4B9D-81DF-494B6333150B} (Minesweeper Flags Class) - http://messenger.zone.msn.com/binary...r.cab31267.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://update.microsoft.com/windowsu...?1124061899656
O16 - DPF: {7E980B9B-8AE5-466A-B6D6-DA8CF814E78A} (MJLauncherCtrl Class) - http://messenger.zone.msn.com/EN-US/...jolauncher.cab
O16 - DPF: {8E0D4DE5-3180-4024-A327-4DFAD1796A8D} (MessengerStatsClient Class) - http://messenger.zone.msn.com/binary...t.cab31267.cab
O16 - DPF: {BD393C14-72AD-4790-A095-76522973D6B8} (CBreakshotControl Class) - http://messenger.zone.msn.com/binary...t.cab31267.cab
O16 - DPF: {D30CA0FD-1CA0-11D4-AC78-006008A9A8BC} (WebBasedClientInstall Class) - https://secure.olemiss.edu/webid_stu/sav9/webinst.cab
O16 - DPF: {DA758BB1-5F89-4465-975F-8D7179A4BCF3} (WheelofFortune Object) - http://messenger.zone.msn.com/binary/WoF.cab31267.cab
O16 - DPF: {F6ACF75C-C32C-447B-9BEF-46B766368D29} (Creative Software AutoUpdate Support Package) - http://www.creative.com/su/ocx/15030/CTPID.cab
O18 - Protocol: skype4com - {FFC8B962-9B40-4DFF-9458-1830C7DD7F5D} - C:\PROGRA~1\COMMON~1\Skype\SKYPE4~1.DLL
O23 - Service: Adobe LM Service - Adobe Systems - C:\Program Files\Common Files\Adobe Systems Shared\Service\Adobelmsvc.exe
O23 - Service: ANIWZCSd Service (ANIWZCSdService) - Wireless Service - C:\Program Files\ANI\ANIWZCS2 Service\ANIWZCSdS.exe
O23 - Service: AntiVir PersonalEdition Classic Scheduler (AntiVirScheduler) - Avira GmbH - C:\Program Files\AntiVir PersonalEdition Classic\sched.exe
O23 - Service: AntiVir PersonalEdition Classic Guard (AntiVirService) - Avira GmbH - C:\Program Files\AntiVir PersonalEdition Classic\avguard.exe
O23 - Service: Apple Mobile Device - Apple, Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: AutoBackup (BMUService) - Memeo - C:\Program Files\Memeo\AutoBackup\MemeoService.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: Java Quick Starter (JavaQuickStarterService) - Sun Microsystems, Inc. - C:\Program Files\Java\jre6\bin\jqs.exe
O23 - Service: lxddCATSCustConnectService - Lexmark International, Inc. - C:\WINDOWS\System32\spool\DRIVERS\W32X86\3\\lxddserv.exe
O23 - Service: lxdd_device - - C:\WINDOWS\system32\lxddcoms.exe
O23 - Service: Nero BackItUp Scheduler 3 - Nero AG - C:\Program Files\Nero\Nero8\Nero BackItUp\NBService.exe
O23 - Service: NMIndexingService - Nero AG - C:\Program Files\Common Files\Nero\Lib\NMIndexingService.exe
O23 - Service: Viewpoint Manager Service - Viewpoint Corporation - C:\Program Files\Viewpoint\Common\ViewpointService.exe
O23 - Service: TrueVector Internet Monitor (vsmon) - Check Point Software Technologies LTD - C:\WINDOWS\system32\ZoneLabs\vsmon.exe

try to download malwarebytes..check if it will help

www.malwarebytes.org

I downloaded Malwarebytes and it found 21 trojans... After removal I had to reset to finish removing 3 of them... then i received the NTLDR missing message when rebooting... After resetting the computer it booted and hung up for a bit... But now all seems to be running smooth and restored! Thanks for the reply Sorry to waste forum space, I was at wits end!

hi jray05stang, no need to be sorry, Daniweb is a friend... anyone is always welcome...
good to hear that your machine is working already..
just surf safely don't go to those sites that are unsafe... to avoid trouble... cheers