Hello,
I would format it into separate partitions for security and managability reasons. Unless you are doing digitial video recording, where you need such a large partition, break that large drive into a few partitions to keep it managable. Yes, there are going to be limits on how large an OS can format a device. There may be other limits on the physical number of files allowed on a drive (for example, can you fill all 128 MB of hard drive with thousands of thousands of 50K (or whatever the smallest cluster size) files?
Partitioning to managable sizes (50 - 100 GB each) protect from these problems. Sometime down the road, you might need to format that partition to fix a problem. If you have your whole drive as one big partition, you might not have anywhere else to go with the data!
If you think of a workstation as a small server, and get out of the One drive = one partition mentality, you will open a lot of doors for new solutions. Granted, partitioning will not save you from a hardware crash of the device, but many logical problems can be avoided.
Christian
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