You can run it (I've never run it personally on a Mac), but due to the Intel processor switchover that occurred a few years ago, Adobe CS2 can't run natively on your Mac, and will have to be emulated using built-in Rosetta technology. This means you'll notice slowdown when running it, and other people have said there are some bugs that occur.
While CS2 will certainly work, if you're serious about running the Adobe suite, your best bet would be to get CS3 for Mac, which supports the Intel processors fully.
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