Hi Sam,
Try this:
RewriteRule ^([A-Za-z]+)/([A-Za-z]+)\.html$ /main.php?Area=$1&Page=$2 [PT,QSA]
Or this (the PT in the example above will make the viewer only see /some/url.html - and NOT /main.php?Area=x&Page=y - if you want the viewer to see/main.php etc remove the PT):
RewriteRule ^([A-Za-z]+)/([A-Za-z]+)\.html$ /main.php?Area=$1&Page=$2 [QSA]
You can find more information here:
http://httpd.apache.org/docs/2.0/mod/mod_rewrite.html
Adnan