I have exactly the same problem as drunknmonkey with perhaps a few extras.
Have only HJT running & fix these entries=
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = about:blank
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,SearchAssistant = about:blank
R1 - HKLM\Software\Microsoft\Internet Explorer\Search,(Default) = about:blank
O2 - BHO: (no name) - {000020DD-C72E-4113-AF77-DD56626C6C42} - (no file)
O2 - BHO: (no name) - {2B1A0B14-8B33-4B96-8E8F-9FF348CB55C0} - C:\WINDOWS\System32\ipxwuan.dll (file missing)
O2 - BHO: (no name) - {4E7BD74F-2B8D-469E-C0FB-EF60B19DA02A} - C:\WINDOWS\System32\wzhelper.dll (file missing)
O2 - BHO: (no name) - {4E7BD74F-2B8D-469E-D7E4-F660B597BF2A} - C:\WINDOWS\System32\webalize.dll (file missing)
O2 - BHO: (no name) - {BCF96FB4-5F1B-497B-AECC-910304A55011} - C:\WINDOWS\hhU.dll
O3 - Toolbar: (no name) - {866D6F83-BCDA-47CA-8D5D-646F5A4E9B78} - (no file)
O3 - Toolbar: WEBALIZE - {4E7BD74F-2B8D-469E-D7E4-F660B597BF2A} - C:\WINDOWS\System32\webalize.dll (file missing)
O3 - Toolbar: (no name) - {014DA6C9-189F-421a-88CD-07CFE51CFF10} - (no file)
O16 - DPF: {1E89F686-B78D-4C85-9EFC-3474516E3FE2} - http://directplugin.com/plugin/113097.exe
O16 - DPF: {56336BCB-3D8A-11D6-A00B-0050DA18DE71} (RdxIE Class) - http://207.188.7.150/08daa6f9f09f57...ip/RdxIE601.cab
O16 - DPF: {5F1ABCDB-A875-46C1-8345-B72A4567E483} - http://www.dotcomtoolbar.com/toolbar_nieuw5.cab
O16 - DPF: {886DDE35-E955-11D0-A707-000000521958} - http://69.56.176.78/webplugin.cab
O16 - DPF: {A7E84D65-E121-4855-8EF0-C96195925F82} (Retriever Class) - http://www.adsvr.net/PowerStrip/PSI.cab
O16 - DPF: {C8BAC37C-A8D2-425E-B7FC-80B9537FB14A} (SBFullS Control) - http://www.spyblast.com/download/SBFullSInst.cab