Since none of the pros are here right now, I'll get you started, but there will be more to fix later.
Close all windows and scan with hijackthis. Have it fix the following entries:
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://qus10.hpwis.com/
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://srch-qus10.hpwis.com/
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = http://srch-qus10.hpwis.com/
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://srch-qus10.hpwis.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://qus10.hpwis.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://srch-qus10.hpwis.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = http://srch-qus10.hpwis.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://srch-qus10.hpwis.com/
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://qus10.hpwis.com/
O2 - BHO: (no name) - {549B5CA7-4A86-11D7-A4DF-000874180BB3} - (no file)
O2 - BHO: (no name) - {FDD3B846-8D59-4ffb-8758-209B6AD74ACC} - (no file)
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\WINDOWS\System32\msjava.dll (file missing)
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\WINDOWS\System32\msjava.dll (file missing)
Reboot, scan again and post a new log.