You should download and run both the AdAware SE and Spyblaster programs. These two coupled with SpyBot S&D will do a good job cleaning up most of the junk. Then, if necessary, go to:
http://www.spychecker.com/download/download_hijackthis.html and download HiJackThis. Be sure to create a new folder for this download. Run the program, save the log file in that folder, and then copy and paste it to here. While I haven't learned just how to best interpret them, there are experts here who can help you. Post the log and we'll try to help. But run the other two programs first to clean up what you can.
There is an excellent tutorial on how to use HiJackThis located at:
http://www.bleepingcomputer.com/forums/tutorial42.html