Get Hijack This there is a download link in my sig and once it is downloaded close all other running apps and scan and save a log and post that log here.

For the About:Blank Search Assistant thing, follow this link to the tutorial:

http://www.besttechie.net/forums/ind...showtopic=1488

It worked for me, hopefully, it will for you too.

As for the popups advertising spyware removers for those popups, that sounds like Messenger service spam. To disable Messenger Service Spam, click Start -> Run. In the box, type in "services.msc". A window will come up with a bunch of stuff listed in it. Go down to where it says "Messenger" and double-click on it. Click on the "STOP" button, then where it says "Startup type:" click the dropdown box and choose either Manual or Disabled. Then X out of all that and you should be done.

You should also do what OurNation says, he's pretty good at doing the HijackThis stuff.

I hope I've helped!