You have a few things there that need removing...
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We'll need to disable (not uninstall) Intermute's SpySubtract, since it might interfere with other program(s) we might be using to 'clean' off your system.
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Run HiJackThis, click "Scan", then check(tick) the following, if present:
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\SearchURL,(Default) = about:blank
R3 - Default URLSearchHook is missing
O2 - BHO: Class - {6B1151A5-E561-1AE7-A73B-D2709D6EC200} - C:\WINDOWS\SYSTEM\D3XF.DLL (file missing)
O4 - HKLM\..\RunServices: [MSQX32.EXE] C:\WINDOWS\SYSTEM\MSQX32.EXE /s
O4 - HKLM\..\RunServices: [APISC32.EXE] C:\WINDOWS\APISC32.EXE /s
O4 - Startup: PowerReg Scheduler.exe
O6 - HKCU\Software\Policies\Microsoft\Internet Explorer\Control Panel present
...(Unless you've set these with a anti-spyware program like SpyBot's Immunize feature, have HiJackThis fix this.)
O9 - Extra button: Related - {c95fe080-8f5d-11d2-a20b-00aa003c157a} - C:\WINDOWS\web\related.htm
O9 - Extra 'Tools' menuitem: Show &Related Links - {c95fe080-8f5d-11d2-a20b-00aa003c157a} - C:\WINDOWS\web\related.htm
O9 - Extra button: (no name) - {E81E083C-979E-49cb-A472-C8F29D7CE8D7} - (no file) (HKCU)
O9 - Extra button: (no name) - {011E1110-AF57-11d4-AC1C-E843E6000000} - (no file) (HKCU)
O16 - DPF: {771A1334-6B08-4A6B-AEDC-CF994BA2CEBE} (Installer Class) - http://static.35mb.com/applet/applet_y.cab
O16 - DPF: {FCF289D4-0AC8-4ED8-BE31-E8AF09606AB5} (download_35mb_com.applet) - http://static.35mb.com/applet/applet_o.cab
O18 - Protocol: relatedlinks - {CD8D1CAA-FE4A-45DF-A06C-028AAF1821DE} - (no file)
Now, with all windows closed except HiJackThis, click "Fix checked".
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Locate and delete the following item(s), if present. Make sure your able to view system and hidden files/ folders:
files...
C:\WINDOWS\SYSTEM\MSQX32.EXE
C:\WINDOWS\APISC32.EXE
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Note that some of these file(s)/folder(s) may or may not be present. If present, and cannot be deleted because they're 'in use', try deleting them in " Safe Mode ".
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Reboot.
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To help protect your system from hostile ActiveX content, or special 'downloadable' files:
Download, install and keep updated, SpywareBlaster . If you've installed it for the first time:
1) Check for any available updates; if present, they'll be automatically downloaded and installed.
2) Next, "Enable all protection".
3) Exit the program.
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Note: Remember to regularly check for updates.
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After rebooting, rescan with hijackthis and post back a new log. Let me know how everything goes.