Hi Michael, welcome to DaniWeb :D
First, right-click in an open area of your desktop and select New, Folder; give the new folder a name (such as HJT or HijackThis), and then drag the hijackthis.exe icon that is on your desktop into the new folder.
Now, scan with HijackThis and have it fix the following entries:
R1 - HKCU\Software\Microsoft\Internet Explorer,(Default) = http://fastsearchweb.com/srh.php?q=%s
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Bar = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = about:blank
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Bar = about:blank
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,Default_Search_URL = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,SearchAssistant = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\Search,CustomizeSearch = about:blank
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = about:blank
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch = about:blank
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,HomeOldSP = about:blank
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,HomeOldSP = about:blank
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = 127.0.0.1; http://localhost
R3 - Default URLSearchHook is missing
O3 - Toolbar: FreshBar - {06ABAA2D-34AB-4902-A326-409BD9B9A7A5} - C:\WINDOWS\system32\iecust.dll
O4 - HKLM\..\Run: [Lisa] C:\Program Files\PInfo\Dialers\Lisa\Lisa.exe /dontdial
O4 - HKLM\..\Run: [HotBlondes] C:\Program Files\PInfo\Dialers\HotBlondes\HotBlondes.exe /dontdial
O4 - HKCU\..\Run: [WareOut] "C:\Program Files\WareOut\WareOut.exe"
O16 - DPF: {0191ABF4-9421-435E-9FFD-CD827A2A82D8} - http://go-in-now.com/tl7000.dll
O16 - DPF: {01A88BB1-1174-41EC-ACCB-963509EAE56B} (SysProWmi Class) - http://support.dell.com/systemprofiler/SysPro.CAB
O16 - DPF: {4ED9DDF0-7479-4BBE-9335-5A1EDB1D8A21} (McAfee.com Operating System Class) - http://bin.mcafee.com/molbin/shared...76/mcinsctl.cab
O16 - DPF: {74D05D43-3236-11D4-BDCD-00C04F9A3B61} (HouseCall Control) - http://a840.g.akamai.net/7/840/537/...all/xscan53.cab
O16 - DPF: {9A9307A0-7DA4-4DAF-B042-5009F29E09E1} (ActiveScan Installer Class) - http://www.pandasoftware.com/activescan/as5/asinst.cab
If either of these IP addresses -- 69.50.176.156 or 195.225.176.31 -- are not related to your ISP, have HJT fix all of the O17 entries.
Close any open windows, other then HijackThis, and hit Fix checked.
Go to the following locations and delete the highlighted file and folders:
C:\WINDOWS\system32\iecust.dll
C:\Program Files\PInfo
C:\Program Files\WareOut
Note: If any of these cannot be deleted, try booting into Safe Mode and deleting them from there.
Reboot (normally), close any open browser windows, scan with HJT, and post a new log please.