Look like you have a trojan and a couple of worms on your computer that could be stealing informaton from your computer. Untill we get this fixed up i would advise that you not go to any online banking sites or anything where you enter personal information.
Ok First run HJT and place a checkmark next to the following.
F0 - system.ini: Shell=Explorer.exe C:\WINDOWS\SYSTEM32\winmgd.win
F1 - win.ini: run=C:\WINDOWS\SYSTEM32\mouse_configurator.win
O2 - BHO: Zango Search Assistant Helper /fleok=1D8A83A5C0E4197F91AB75760EA83FA5EF80752B94E2DF7E5B7E472D37C3 - {56F1D444-11BF-4879-A12B-79CF0177F038} - c:\program files\zango\zangohook.dll (file missing)
O4 - HKLM\..\RunServices: [WinProfile] sndcfg16.exe
O4 - HKLM\..\RunServices: [RDLL] RunDll16.exe
Now click fix checked.
You might want to print out the following instructions as you will not be able to access the internet from safe mode.
Reboot your computer and while it is loading continuously tap F8 until a menu pops up. Use the arrows key to select safe mode and then hit enter.
Once in safe mode use My Computer to locate and delete the following folders/files.
C:\WINDOWS\SYSTEM32\winmgd.win
C:\WINDOWS\SYSTEM32\mouse_configurator.win
c:\program files\zango\
The last two files you'll have to find they are either in the C:\Windows\ directory or C:\Windows\System\ or C:\Windows\System32\ directory. Those are the following files.
sndcfg16.exe
RunDll16.exe
Now reboot back to normal.
Post a new HJT log along with any problems your still having in your next post.