Okay, running blind here, but may I suggest you copy these two files to a replaceable drive .. eg pen drive, CDRW... install and run them?
==Get CCleaner from http://www.ccleaner.com/ - and put it in a new folder. You should aim to keep this one for general use. I set the installation checkboxes only to open from the recycle bin. It's neater that way.
Now run CCleaner from the recycle bin rclick menu using its default settings [if you set up CCleaner as i suggested, rclicking the bin icon should give you the Open CCleaner option...]. Select the Cleaner icon, press Run Cleaner.
[For future quick temp file cleaning select the options you wish to use via the Windows and Applications tabs ..]
==Download this file to your desktop: http://download.bleepingcomputer.com/sUBs/ComboFix.exe
- to run it dclick combofix.exe and follow the prompts to start it. When finished, it will produce a log, C:\Combofix.txt - post that log in your next reply.
A word of caution - do not touch your mouse/keyboard until the scan has completed. The scan will temporarily disable your desktop, and if interrupted may leave your desktop disabled. If this occurs, please reboot to restore the desktop.
Post the result...