By freezing you mean it locks up? You can not do anything? Start menu? Alt + Tab ? Ctrl + Alt + Del (i.e. bring up task manager) ?
And no problems with either drive other than the mentioned issue?
How are the drives connected? (IDE, SCSI, USB) ?
What type of file, and how are you moviing it? i.e. command prompt, windows explorer, window to window?
Have you tried to just copy it? Is so, do you get the same result?