I have to add to this. I had a day which I did a bunch of updates to my XP x64 install- Windows updates, defrag, registry clean, and spyware sweep. A day or two later my Office suite (Word and Excel in particular) were running extremely slow. The apps would take sometimes minutes before they would pull open.
The other thing I started noticing was that links from Windows Live Messenger as well as Outlook also started experiencing these painful slowdowns.
My system specs are pretty high currently.
I have a custom built:
8 gigs DDR RAM
Dual Quad Core Core 5160s
So, there's really no reason why any of this should be running slow.
My first instinct was that it was a virus so I scanned for that several times. Then secondly, I thought it may have been the new AVG causing this - I uninstalled and still had these issues.
Over time, I realized that if opened up the process manager, it would often kick in/start up these applications. It was weird, but it worked some of the time.
Finally, I came across this thread. The problem is such a generic term that it is almost like finding a needle in a haystack.
I disabled DDE for this and suddenly my computer is back to normal again regarding the links. It actually seems better (and much faster) than ever.
I will have to wait a few days and see how the rest of the Office suite performs.
Thanks again for the help here. I thought it was my imagination or something which I screwed up somehow.