You have to create a profile before you can do anything with outlook. Simple way of doing this is to go to >> control panel >> select 'mail' by double clicking >> show profiles button >> add a new profile

Outlook will take you through a wizard which will allow you to plug in your info such as smtp server and/or pop server. Afterwards you should be all set. Don't forget to make sure you have Outlook using the right profile...go back into control panel >> mail >> and look to make sure outlook is using the right profile at the bottom of the popup window.