...The best tool you can have though in the end, is yourself. Get to know your system... the ability to sense when things are not running as they should (ie, high memory usage when little seen to be running). Better yet, learning how to KEEP your system safe by your own practices, rather than over relying on the OS and 3rd party anti-malware utilities to keep your system secure - which can almost lead to a false sense of security.
IMHO it's easy enough to know when things aren't running right. And keeping your system right by your own practices is as sound a piece of advice as Rik's perfect contribution.
I'd put myself in that category and yet, without McAfee, Ad-aware and Anti-Malware I'd be up sh*t creek, There are many so-called safe sites who have unbeknown malware embedded somewhere in their servers. Cookies are a real risk but you can't stop them and still do reasonable stuff.
I rely totally on McAfee and Ad-Aware to block trojans and unexpected registry entries;the anti-malwarebytes (which I pay for) to scan every time I "feel" something's not right.
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