Is there a way, in Windows Vista, to prevent certain programs from saving files to a certain folder?

The reason I ask, is I recently opened a document from an email, made a bunch of changes, and saved it, not realizing it had saved to the Temp folder. Later, unable to locate the saved version, I opened it again from the email, thus overwriting the changes that were in the saved version. I do not want to do this again! I want to receive some sort of warning that will prevent me from accidentally saving files to the Temp folder.

So I thought, if I could deny that privilege to Word, and Acrobat, and a few other programs I commonly use to open email attachments, that might do the trick. However, I'm open to any other suggestions that might keep me safe from my own stupidity!

Thanks!