-Power supply calculator-
http://www.extreme.outervision.com/index.jsp
This only gives you a minmum wattage requirement, however, the amperage on each of the rails is what's important, and one must keep in mind that for most power supplies, one can't max the current capacity of both the 5v and 12v rails.
Ok now before you go charging off to go get the 500 watt power supply for 12 dollars on ebay there are a couple things to think about. You want to check to make sure that the PSU is made by a well know company (we will get in to that later). The PSU must be AMD, Intel & UL listed. What’s UL? Google it. Last, and very important, the PSU must supply at least 18A on the +12V rail.
I don't want you to be mislead by the calculator I provided above. While it does add up your total power consumption during peak use, it does not help you in picking out the correct power supply. I can not emphasize enough do not base you decision on wattage alone.
That said what else can you do to ensure you will live power trouble free? One of the easiest ways is to stick to the quality brands (which often means more money but less headache). So what are the quality brands? There are quite a few but to name a couple: PC Power and Cooling, Enermax, Sparkle, Antec (TruePower).
A couple of things to distinguish the big boys is temperature and efficiency which kinda go hand in hand. The more efficient it is then the less power it will lose as heat. Also, look for the little extras like adjustable rails, detachable rails, decibel level... etc.
The PSU is easy to skimp on, but if you are a serious overclocker, don't.