Yes, there are different types of motherboards (called chipsets. AMD, Nvidia and Intel each have their own chipsets) and then different brands. Many brands (ASUS, MSI etc.) will make their own model, based on a certain chipset.

You're right, the motherboard is the most important choice, but what motherboard you choose will depend on what you want to plug into it.

If you mean an intel Core2Quad, then you're looking at these chipsets: P35, P45, X38, X48, 750i, 780i, 790i. I'm sure there's more, but they spring to mind. The 750i etc. are SLI ones (2 or more Nvidia cards) so they're no use to you with an ATI card.

That leaves you with the P35, P45, X38 or X48 (both Intel chipsets). The newer X48 has DDR3 versions, which is the type of RAM. DDR3 is a little better than DDR2 RAM, but also a little more expensive.

The new Intels are the i7s which require a different motherboard chipset again, the X58. These also require DDR3 RAM.
Here's a quick discussion about it:
http://forums.techguy.org/hardware/8...eproofing.html

Post a specific question and I'm sure someone will get back to you

In regards to the ATI Vs Nvidia card usage, you can use an ATI card on an Nvidia chipset motherboard. The only thing you cannot do is crossfire two or more ATI cards on the Nvidia chipset board.
The same goes for an AMD chipset board. You can use a single Nvidia card, but you cannot SLi them.

Thank you for your replies, TNN and crunchie,

So would you recommend that an INTEL CPU be paired with a NVIDIA Chipset Motherboard and NVIDIA Video Card? And an AMD CPU be paired with an AMD Chipset Motherboard and ATI Video Card?

Any recommendations for pairings? I'll be using this computer for Adobe Creative Suite 3 (Photoshop, Illustrator, Dreamweaver) as well as playing Champions Online and City of Heroes. And will most likely go with Windows 7 as the OS.

Well, for one thing there are different sizes. There are Midi-ATX, Full ATX and Micro-ATX. Make sure you get the right one to fit in your case.

Also get the one with the right socket type for your CPU

I'd recommend an Intel CPU. AMD are coming back, but are not quite there as far as I can tell.

I'd recommend an Nvidia GPU, but ATI graphics cards really are just as good, I'm just an Nvidia person

I would not recommend an Nvidia chipset motherboard. They're good if you like playing with stuff (as I do) but you can't go past a solid Intel chipset.

Yeah. SLI is overrated anyway.