Reinstall the motherboard chipset drivers, check to ensure that Windows updates are loaded, then reinstall any necessary USB 2.0 drivers or patches from the motherboard website.
It sounds like a problem which relates to their installation withing Windows rather than a hardware problem.
If they are front panel connectors, however, it would be well to ensure the cables are firmly connected to the motherboard header, and haven't worked loose.
Catweazle
Grandad
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