NargalaX 8 Junior Poster in Training

I'm making a game board style program (Basically a modified monopoly with automated pieces and questions) and it is currently in the very early stages.

Right now I am making the gameboard pieces move properly etc., but once I'm finished that I will need to know how to check if an object is in the 2d area of another object.

The monopoly pieces are pictureboxes, and I will have transparent pictureboxes labeled as the designated monopoly places etc., (the board is a single image, thats why I must do that).

How could I accomplish this, simply?