You can create custom ribbons. They are stored under the Add-Ins tab.
Create a project for Office [office product - Excel, Word, ..] Add-In.
Add a ribbon to the project from the Office group. Use the designer selection.
Add as many groups to the ribbon as will visuall fit. Add buttons, labels, etc to each group. Hook the button click events to do what you want to do in code just like a button event in Winforms or Webforms.
Here is an overview:
http://msdn.microsoft.com/en-us/magazine/cc163403.aspx
Good luck.