Mac OS X provides built-in support for Java applets. You don't have to do anything special to set this up--just run Netscape under OS X and you should be able to run the BioViews applets.
The best browser for running Java applets is Internet Explorer 5.1 or above. You can use Netscape 6.2, but it doesn't work as well.
Instructions
Java programs such as the BioViews map viewers run inside software called the "Java Virtual Machine," or JVM. All Java-capable browsers come with a JVM, but Internet Explorer is the only browser for the Mac that lets you pick the JVM that works best on your machine. The best JVM for pre-OS X Macs, buggy though it may be, is the Macintosh Java Runtime from Apple. (We have contacted Apple about the problems with the MRJ, and they are aware of the problems, but they do not consider it a priority to repair these problems.)
If you're running MacOS 8 or 9, we recommend you run our BioViews java tools using Apple's MRJ 2.1 teamed with Internet Explorer 4.5 or higher. Unfortunately, more recent versions of the MRJ are buggy and do not work properly with IE or Netscape. (Some users have gotten good results running GeneSeen with the latest MRJ version, but it does not work consistently.)
Downloading link
You should be able to download MRJ 2.1.4 from apple.com . In case that link stops working, we have saved local (untested!) copies of the MRJ 2.1.4 in two different formats:
* MRJ_2.1.4.smi.bin
* MRJ_2.1.4.smi.hqx
If you don't have Internet Explorer, get a copy of IE 4.0 or higher from http://www.microsoft.com/Mac/ie and install it on your machine. Internet Explorer will detect that you have installed the MRJ, and will automatically use it.
If you already have IE 4.0 or 4.5 installed, you should make sure that it is using the MRJ instead of the built-in Java interpreter. To do this, pick "Preferences" from the "Edit" menu. Go to the Java section of the preferences screen. Make sure that "enable Java" is clicked, and make sure that "Apple MRJ" is the selected Java virtual machine.
Configration:
After you install both Internet Explorer 4.5 and Apple's MRJ 2.1.4, you need to tell Internet Explorer to use Apple's MRJ.
To do this, double-click the Internet Explorer icon. Next, click the "preferences" icon at the top left - it looks like a folder. Under "Web Browser," select the option labeled "Java." Under "Java Options," chose "Apple MRJ" from the menu labeled "Java virtual machine."
Restart your browser. The next time you visit our Web site using Internet Explorer 4.5 or higher, you should be able to run our Java applets.
I hope this may help you solve your problem running applet on mac
