I started out with Tkinter for my GUI stuff, but tend to use wxPython more and more. wxPython is more up to date (more fancy widgets) and gives me more control over the placement of the widgets/components.
vegaseat
DaniWeb's Hypocrite
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wxGlade looks interesting too. I ended up with a copy of it when I downloaded movablePython. It is a plugin for the SPE editor.
If I am too lazy to build my own wxPython forms, I use BOA Constructor's form builder option. I don't think BOA works with Linux though.
vegaseat
DaniWeb's Hypocrite
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