I have started programming in python . I want to know the best GUI binding to use .pyqt and wxpython which one is the best and easy to learn and install on federa 13

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If you are using Gnome -> use wxpython.
If you are using KDE -> use Qt4.

Look at the code examples given in the other thread called "Python GUI Programming."
One of the GUI tool kits there might suit your taste or needs. Other than Tkinter, most GUI toolkits for Python are wrappers for code written in C++.

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