You can insert a print statement for testing the progress, and see how the higher values bubble to the end and lower values bubble to the start of the list:
myList=[43,21,12,80,3,2,35]
print(myList)
print('-'*30)
end = len(myList)-1
while (end != -1):
swapped = -1
for i in range(0, end):
if myList[i] > myList[i+1]:
temp = myList[i]
myList[i] = myList[i+1]
myList[i+1]= temp
print(myList) # test print to follow progress of sort
swapped = i
end = swapped
print('-'*30)
print(myList)
'''
[43, 21, 12, 80, 3, 2, 35]
------------------------------
[21, 43, 12, 80, 3, 2, 35]
[21, 12, 43, 80, 3, 2, 35]
[21, 12, 43, 3, 80, 2, 35]
[21, 12, 43, 3, 2, 80, 35]
[21, 12, 43, 3, 2, 35, 80]
[12, 21, 43, 3, 2, 35, 80]
[12, 21, 3, 43, 2, 35, 80]
[12, 21, 3, 2, 43, 35, 80]
[12, 21, 3, 2, 35, 43, 80]
[12, 3, 21, 2, 35, 43, 80]
[12, 3, 2, 21, 35, 43, 80]
[3, 12, 2, 21, 35, 43, 80]
[3, 2, 12, 21, 35, 43, 80]
[2, 3, 12, 21, 35, 43, 80]
------------------------------
[2, 3, 12, 21, 35, 43, 80]
'''
Also the C type swap
temp = myList[i]
myList[i] = myList[i+1]
myList[i+1]= temp
can be replaced with a Python tuple swap
myList[i+1], myList[i] = myList[i], myList[i+1]