Write a file based DSN that points to your file and then use it in the connection string.
[Example DSN]
[ODBC]
DRIVER=Driver do Microsoft Excel(*.xls)
UID=admin
UserCommitSync=Yes
Threads=3
SafeTransactions=0
ReadOnly=1
PageTimeout=5
MaxScanRows=8
MaxBufferSize=2048
FIL=excel 8.0
DriverId=790
DefaultDir={place app path here}
DBQ={place app path here}\Document.xls
Use your ODBC control Panel to creat the base DSN to your file as the info changes with each version of Excel.
I've never re-linked like this, but theoretically, you should be able to write a VB Module within Access to open the link.