I need a help on VB 2008. How can make a button enable or visible when only the datagridview's only 1 check box is checked?

inside your checkbox_CheckChanged method do this:

if(checkBox.checked) {
  button1.enable = true;
  or button1.visible = true;
} else {
  button1.enable = false;
  or button1.visible = false;
}

Thats c# code anyway. You get the idea

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