If I load a text file as the source of an IFrame, how do I save any client side changes to it back to the server?

you can not because it wont be editable anyway. instead of that you can use what you see is what you get editor, and use it as a standart web control

Thank you for your reply. I tried using an iframe with just a text file as a source yesterday and found out that it is read only.

I have never heard of a wysiwyg editor. Are you saying that what I want to do is possible, just with a different approach?

yeah of cource, search google with asp.net wsiwyg or rich text editor, there lots of them for free, and you can use them like all other web server controls.

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