I tried to shut down via the Start> Shut Down> Shut Down and nothing happened. I can't open any shortcuts (they get sort of greyed out), I had to open Firefox by entering google.com in the "My Documents" folder's address bar. And can't open the anti-virus (avast!). I think it started when I download and extracted "Portable Microsoft Publisher 2003 en Español" rar file, the anti-virus detected a virus called CLOSE PROCESS or CERRAR PROCESOS (because the file was in Spanish). I selected the "Move it to Chest" option and all was fine till now.
I ran Hijack and this is the log:

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 11:04:30 PM, on 4/17/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.6000.16640)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
C:\Program Files\Alwil Software\Avast4\ashServ.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
C:\WINDOWS\RTHDCPL.EXE
C:\Program Files\iTunes\iTunesHelper.exe
C:\Program Files\Java\jre1.6.0_05\bin\jusched.exe
C:\Program Files\Seagate\DiscWizard\DiscWizardMonitor.exe
C:\Program Files\Seagate\DiscWizard\TimounterMonitor.exe
C:\Program Files\Common Files\Seagate\Schedule2\schedhlp.exe
C:\Program Files\ATI Technologies\ATI.ACE\Core-Static\MOM.exe
C:\Program Files\Logitech\iTouch\iTouch.exe
C:\Program Files\Common Files\Seagate\Schedule2\schedul2.exe
C:\Program Files\APC\APC PowerChute Personal Edition\mainserv.exe
C:\Program Files\YourWare Solutions\FreeRAM XP Pro\FreeRAM XP Pro.exe
C:\Program Files\DAEMON Tools Lite\daemon.exe
C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
C:\Program Files\Common Files\Autodesk Shared\Service\AdskScSrv.exe
C:\Program Files\Bonjour\mDNSResponder.exe
C:\Program Files\Autodesk\3ds Max 9\mentalray\satellite\raysat_3dsmax9_32server.exe
C:\Program Files\APC\APC PowerChute Personal Edition\apcsystray.exe
C:\WINDOWS\system32\svchost.exe
C:\Program Files\ATI Technologies\ATI.ACE\Core-Static\ccc.exe
C:\Program Files\Alwil Software\Avast4\ashMaiSv.exe
C:\Program Files\Alwil Software\Avast4\ashWebSv.exe
C:\Program Files\iPod\bin\iPodService.exe
C:\Program Files\Common Files\Real\Update_OB\realsched.exe
C:\Documents and Settings\WINDOWS XP.USER\Desktop\Portable Microsoft Publisher 2003 en Español\Portable Microsoft Publisher 2003 en Español\AutoPlay\Docs\MSPUB.EXE
C:\WINDOWS\system32\logonui.exe
C:\PROGRA~1\MOZILL~1\FIREFOX.EXE
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
O2 - BHO: (no name) - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - (no file)
O2 - BHO: (no name) - {3049C3E9-B461-4BC5-8870-4C09146192CA} - (no file)
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - (no file)
O2 - BHO: (no name) - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - (no file)
O2 - BHO: (no name) - {7E853D72-626A-48EC-A868-BA8D5E23E045} - (no file)
O2 - BHO: (no name) - {9030D464-4C02-4ABF-8ECC-5164760863C6} - (no file)
O2 - BHO: Payya Tec Popup Killer - {C68AE9C0-0909-4DDC-B661-C1AFB9F5AE53} - (no file)
O4 - HKLM\..\Run: [avast!] C:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
O4 - HKLM\..\Run: [RTHDCPL] RTHDCPL.EXE
O4 - HKLM\..\Run: [Alcmtr] ALCMTR.EXE
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\QTTask.exe" -atboottime
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre1.6.0_05\bin\jusched.exe"
O4 - HKLM\..\Run: [DiscWizardMonitor.exe] C:\Program Files\Seagate\DiscWizard\DiscWizardMonitor.exe
O4 - HKLM\..\Run: [AcronisTimounterMonitor] C:\Program Files\Seagate\DiscWizard\TimounterMonitor.exe
O4 - HKLM\..\Run: [Acronis Scheduler2 Service] "C:\Program Files\Common Files\Seagate\Schedule2\schedhlp.exe"
O4 - HKLM\..\Run: [StartCCC] "C:\Program Files\ATI Technologies\ATI.ACE\Core-Static\CLIStart.exe"
O4 - HKLM\..\Run: [zBrowser Launcher] C:\Program Files\Logitech\iTouch\iTouch.exe
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
O4 - HKCU\..\Run: [FreeRAM XP] "C:\Program Files\YourWare Solutions\FreeRAM XP Pro\FreeRAM XP Pro.exe" -win
O4 - HKCU\..\Run: [AlcoholAutomount] "E:\Program Files\Alcohol Soft\Alcohol 52\axcmd.exe" /automount
O4 - HKCU\..\Run: [DAEMON Tools Lite] "C:\Program Files\DAEMON Tools Lite\daemon.exe" -autorun
O4 - HKCU\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [IE New Window Maximizer] C:\Program Files\IE New Window Maximizer\iemaximizer.exe
O4 - HKCU\..\Run: [AdobeUpdater] C:\Program Files\Common Files\Adobe\Updater5\AdobeUpdater.exe
O4 - HKCU\..\Run: [Sony Ericsson PC Suite] "C:\Program Files\Sony Ericsson\Sony Ericsson PC Suite\SEPCSuite.exe" /systray /nologon
O4 - HKUS\S-1-5-21-789336058-57989841-725345543-1003\..\Run: [FreeRAM XP] "C:\Program Files\YourWare Solutions\FreeRAM XP Pro\FreeRAM XP Pro.exe" -win (User '?')
O4 - HKUS\S-1-5-21-789336058-57989841-725345543-1003\..\Run: [AlcoholAutomount] "E:\Program Files\Alcohol Soft\Alcohol 52\axcmd.exe" /automount (User '?')
O4 - HKUS\S-1-5-21-789336058-57989841-725345543-1003\..\Run: [DAEMON Tools Lite] "C:\Program Files\DAEMON Tools Lite\daemon.exe" -autorun (User '?')
O4 - HKUS\S-1-5-21-789336058-57989841-725345543-1003\..\Run: [SpybotSD TeaTimer] C:\Program Files\Spybot - Search & Destroy\TeaTimer.exe (User '?')
O4 - HKUS\S-1-5-21-789336058-57989841-725345543-1003\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe (User '?')
O4 - HKUS\S-1-5-21-789336058-57989841-725345543-1003\..\Run: [IE New Window Maximizer] C:\Program Files\IE New Window Maximizer\iemaximizer.exe (User '?')
O4 - HKUS\S-1-5-21-789336058-57989841-725345543-1003\..\Run: [AdobeUpdater] C:\Program Files\Common Files\Adobe\Updater5\AdobeUpdater.exe (User '?')
O4 - HKUS\S-1-5-21-789336058-57989841-725345543-1003\..\Run: [Sony Ericsson PC Suite] "C:\Program Files\Sony Ericsson\Sony Ericsson PC Suite\SEPCSuite.exe" /systray /nologon (User '?')
O4 - Global Startup: Adobe Reader Speed Launch.lnk = C:\Program Files\Adobe\Acrobat 7.0\Reader\reader_sl.exe
O4 - Global Startup: APC UPS Status.lnk = ?
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O9 - Extra button: Popup Killer Options - {0D555BC6-E331-48b3-A60E-AAC0DF79438A} - C:\WINDOWS\system32\shdocvw.dll
O9 - Extra 'Tools' menuitem: Popup Killer - {0D555BC6-E331-48b3-A60E-AAC0DF79438A} - C:\WINDOWS\system32\shdocvw.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - C:\WINDOWS\Network Diagnostic\xpnetdiag.exe
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://www.update.microsoft.com/windowsupdate/v6/V5Controls/en/x86/client/wuweb_site.cab?1203742407468
O23 - Service: Acronis Scheduler2 Service (AcrSch2Svc) - Acronis - C:\Program Files\Common Files\Seagate\Schedule2\schedul2.exe
O23 - Service: APC UPS Service - American Power Conversion Corporation - C:\Program Files\APC\APC PowerChute Personal Edition\mainserv.exe
O23 - Service: Apple Mobile Device - Apple, Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: avast! iAVS4 Control Service (aswUpdSv) - ALWIL Software - C:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
O23 - Service: Ati HotKey Poller - ATI Technologies Inc. - C:\WINDOWS\system32\Ati2evxx.exe
O23 - Service: ATI Smart - Unknown owner - C:\WINDOWS\system32\ati2sgag.exe
O23 - Service: Autodesk Licensing Service - Autodesk - C:\Program Files\Common Files\Autodesk Shared\Service\AdskScSrv.exe
O23 - Service: avast! Antivirus - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashServ.exe
O23 - Service: avast! Mail Scanner - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashMaiSv.exe
O23 - Service: avast! Web Scanner - ALWIL Software - C:\Program Files\Alwil Software\Avast4\ashWebSv.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: FLEXnet Licensing Service - Macrovision Europe Ltd. - C:\Program Files\Common Files\Macrovision Shared\FLEXnet Publisher\FNPLicensingService.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: mental ray 3.5 Satellite (32-bit) (mi-raysat_3dsmax9_32) - Unknown owner - C:\Program Files\Autodesk\3ds Max 9\mentalray\satellite\raysat_3dsmax9_32server.exe
O23 - Service: Pml Driver HPZ12 - HP - C:\WINDOWS\system32\HPZipm12.exe

--
End of file - 10207 bytes

Please Help! :(

I was in fact a file called "cerrar procesos.exe" (close processes in spanish) that caused the problems. What can I do, I can't open most applications like anti-virus, Process Monitor, and I'm afraid to shut down manually and then the computer won't start up. Please help.

I suggest manually shutting off the computer (hold power button till powers off)
Then when the pc is booting Press f8 before the boot screen to give the option of safe mode boot, go into safe mode and run your antivirus scanner. Another good program is trojan remover. Where some of the top internet secutrity programs simply delete the bad file trojan remover will reverse the changes the virus made to settings and other files. You can also use this in combination with other is programs.

Clean first:
==Get CCleaner from http://www.ccleaner.com/ - and install it in a new folder. You should keep this one for general use. I set the installation checkboxes only to open from the recycle bin. It's neater that way.
Now run CCleaner from the recycle bin rclick menu using its default settings [if you set up CCleaner as i suggested, rclicking the bin icon should give you the Open CCleaner option...].
If you have FireFox open the Applications tab and ensure at least that Cookies and Cache are checked.
Select the Cleaner icon, press Run Cleaner.
[For future quick temp file cleaning select the options you wish to use via the Windows and Applications tabs ..]
Now scan:
==Please use IE or Firefox to do an online scan at panda:- http://www.pandasecurity.com/homeusers/solutions/activescan/?
-for the free online virus scan select the link Scan your PC, then Register [otherwise there will be no disinfection, merely detection] with a valid email and follow through.
Post the log it produces here.

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