http://nambulous.wordpress.com/2008/08/23/remove-the-net-framework-assistant-10-from-firefox/
Why do I need it?

Why didn't you ask me?
- I agreed to your necessary maintenance of your OS, not for you to modify any 3rd party applications which happen to be on the machine to suit your purposes (put that in your EULA).

Why is "Uninstall" disabled?

OMG! It has come to the point that I don't give any of MS' programs blanket permission to pass ZoneAlarm - I would rather be bothered each time than to let them start taking over my system (any more than it already has). But I am paranoid(ish).

With all these additional 'forced users' maybe Microsoft stock will go up for a change? I am stuck with Vista at work and at home, and I hate it!