Best Method To update a Record

[luckyismb]

Hello
I have two tables, ItemsInforamtion and MachinaryDetail
i insert a record like this
1-ItemCode,EntryDate, Category, SubCategory,RecQty,IssuedQty,Balance (ItemsInformation)
1 2/11/2001 Machinary Server 3 0 3
2-SerailNumber, Description, Vendor(MachinaryDetail)
fffeeee sdsfsfs IBM (Grid Combo Box)
sdfsfs ssfsfsfs IBM
sdfsfd sdfsfsf DEL
while ItemCode is Primary key in Itemsinforation table and F.K in Machinarydetail table.
ItemCode is autonumber i.e 1,2,3,4.....
After Saving Grid and all other controls make clear
After Saving the record i want to update or delete this data which one is the best method.
how to handle GridCombo box while updating