I am using a licensed version of VS 2010 Express and I created a simple program.
The program has 1 Class, 4 methods(So Far), 10 Buttons, and 1 Pop Up Box. When I try to run/debug the program, the locks appear next to my opened files and it says "(Running)" in the top left. It stays like this for a long time, and doesn't open a new window with my Form in it. Without any code and just the form with 10 buttons it ran fine. Any ideas on what might have caused this, or does debugging usually take this long?

When it's running, click on debug->break all. This will stop the program and show you the current line that is running. If that line (and the lines around it) don't explain your issue, post the code here.