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This problem all started when I bought, installed, and then tried to get Starcraft 2 to work with my video card. Suddenly I am being plagued by a multitude of problems. The first, and possibly most annoying, is everytime I launch internet explorer I get a runtime 217 error, and after clicking on "Check online and close program" it works just fine.

Second problem, which actually may be causing my runtime error, last night my virus scanner (Comodo) went over protective by itself and was blocking everything. It also reported that internet explorer was trying to gain full access the keyboard, and I suspect a potential keylogger.

A third problem involves opening Microsoft Office files. Everytime I try to open these files I get an error message, and have to open the file a second time to actually get it to open.

Problem four involves my mouse beginning to double click by itself. I have checked the settings and nothing like this should be happening. I did remove a few startup programs that involved my usb wireless mouse, but they should have only been the adware from Logitech.

Lastly, after trying to free up some much needed space on my system I ran a defrag on my system. When the defrag finished it told me that I needed to run another defrag. And another. And another...

I have no idea what kind of gremlins are infesting my machine, but Spybot search and destroy does not catch it, and neither does Comodo, F-Secure, or Malware Bytes. I've ran Check Disk with no results, and am out of ideas. Please help.

Below I have included my latest Hijackthis log file:

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 9:04:00 AM, on 10/08/2010
Platform: Windows Vista SP2 (WinNT 6.00.1906)
MSIE: Internet Explorer v8.00 (8.00.6001.18928)
Boot mode: Normal

Running processes:
C:\Windows\system32\taskeng.exe
C:\Windows\system32\Dwm.exe
C:\Windows\Explorer.EXE
C:\Program Files\Windows Defender\MSASCui.exe
C:\Program Files\COMODO\COMODO Internet Security\cfp.exe
C:\Program Files\Windows Sidebar\sidebar.exe
C:\Program Files\Logitech\SetPoint\SetPoint.exe
C:\Program Files\NVIDIA Corporation\nTune\nTuneCmd.exe
C:\Program Files\Common Files\Logishrd\KHAL2\KHALMNPR.EXE
C:\Program Files\Windows Sidebar\sidebar.exe
C:\Program Files\Spybot - Search & Destroy\SpybotSD.exe
C:\Program Files\Trend Micro\HijackThis\HijackThis.exe
C:\Windows\system32\SearchFilterHost.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName =
O1 - Hosts: ::1 localhost
O2 - BHO: (no name) - {02478D38-C3F9-4efb-9B51-7695ECA05670} - (no file)
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: Spybot-S&D IE Protection - {53707962-6F74-2D53-2644-206D7942484F} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O2 - BHO: SMART Notebook Download Plugin - {67BCF957-85FC-4036-8DC4-D4D80E00A77B} - C:\Program Files\SMART Technologies\SMART Notebook\NotebookPlugin.dll
O2 - BHO: Windows Live ID Sign-in Helper - {9030D464-4C02-4ABF-8ECC-5164760863C6} - C:\Program Files\Common Files\Microsoft Shared\Windows Live\WindowsLiveLogin.dll
O2 - BHO: Google Toolbar Notifier BHO - {AF69DE43-7D58-4638-B6FA-CE66B5AD205D} - C:\Program Files\Google\GoogleToolbarNotifier\5.1.1309.3572\swg.dll
O2 - BHO: Java(tm) Plug-In 2 SSV Helper - {DBC80044-A445-435b-BC74-9C25C1C588A9} - C:\Program Files\Java\jre6\bin\jp2ssv.dll
O3 - Toolbar: (no name) - {CCC7A320-B3CA-4199-B1A6-9F516DD69829} - (no file)
O4 - HKLM\..\Run: [Windows Defender] %ProgramFiles%\Windows Defender\MSASCui.exe -hide
O4 - HKLM\..\Run: [Kernel and Hardware Abstraction Layer] KHALMNPR.EXE
O4 - HKLM\..\Run: [NVHotkey] rundll32.exe C:\Windows\system32\nvHotkey.dll,Start
O4 - HKLM\..\Run: [COMODO Internet Security] "C:\Program Files\COMODO\COMODO Internet Security\cfp.exe" -h
O4 - HKCU\..\Run: [Sidebar] C:\Program Files\Windows Sidebar\sidebar.exe /autoRun
O4 - HKUS\S-1-5-19\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-19\..\Run: [WindowsWelcomeCenter] rundll32.exe oobefldr.dll,ShowWelcomeCenter (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-20\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'NETWORK SERVICE')
O4 - Global Startup: Logitech SetPoint.lnk = C:\Program Files\Logitech\SetPoint\SetPoint.exe
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~3\Office12\EXCEL.EXE/3000
O8 - Extra context menu item: Send To &Bluetooth - C:\Program Files\WIDCOMM\Bluetooth Software\btsendto_ie_ctx.htm
O9 - Extra button: @C:\Program Files\Windows Live\Writer\WindowsLiveWriterShortcuts.dll,-1004 - {219C3416-8CB2-491a-A3C7-D9FCDDC9D600} - C:\Program Files\Windows Live\Writer\WriterBrowserExtension.dll
O9 - Extra 'Tools' menuitem: @C:\Program Files\Windows Live\Writer\WindowsLiveWriterShortcuts.dll,-1003 - {219C3416-8CB2-491a-A3C7-D9FCDDC9D600} - C:\Program Files\Windows Live\Writer\WriterBrowserExtension.dll
O9 - Extra button: Send to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MICROS~3\Office12\ONBttnIE.dll
O9 - Extra 'Tools' menuitem: S&end to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MICROS~3\Office12\ONBttnIE.dll
O9 - Extra button: (no name) - {85d1f590-48f4-11d9-9669-0800200c9a66} - C:\Windows\bdoscandel.exe (file missing)
O9 - Extra 'Tools' menuitem: Uninstall BitDefender Online Scanner v8 - {85d1f590-48f4-11d9-9669-0800200c9a66} - C:\Windows\bdoscandel.exe (file missing)
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~3\Office12\REFIEBAR.DLL
O9 - Extra button: (no name) - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O9 - Extra 'Tools' menuitem: Spybot - Search & Destroy Configuration - {DFB852A3-47F8-48C4-A200-58CAB36FD2A2} - C:\PROGRA~1\SPYBOT~1\SDHelper.dll
O13 - Gopher Prefix:
O15 - Trusted Zone: http://www.adobe.com
O16 - DPF: Garmin Communicator Plug-In - https://static.garmincdn.com/gcp/ie/2.9.2.0/GarminAxControl.CAB
O16 - DPF: {E2883E8F-472F-4FB0-9522-AC9BF37916A7} - http://platformdl.adobe.com/NOS/getPlusPlus/1.6/gp.cab
O18 - Protocol: bwfile-8876480 - {9462A756-7B47-47BC-8C80-C34B9B80B32B} - C:\Program Files\Logitech\Desktop Messenger\8876480\Program\GAPlugProtocol-8876480.dll
O20 - AppInit_DLLs: C:\Windows\system32\guard32.dll
O22 - SharedTaskScheduler: Windows DreamScene - {E31004D1-A431-41B8-826F-E902F9D95C81} - C:\Windows\System32\DreamScene.dll
O23 - Service: Apple Mobile Device - Apple Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\AppleMobileDeviceService.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: COMODO Internet Security Helper Service (cmdAgent) - COMODO - C:\Program Files\COMODO\COMODO Internet Security\cmdagent.exe
O23 - Service: Google Software Updater (gusvc) - Google - C:\Program Files\Google\Common\Google Updater\GoogleUpdaterService.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\1050\Intel 32\IDriverT.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: Logitech Bluetooth Service (LBTServ) - Logitech, Inc. - C:\Program Files\Common Files\Logitech\Bluetooth\LBTServ.exe
O23 - Service: LexBce Server (LexBceS) - Lexmark International, Inc. - C:\Windows\System32\LEXBCES.EXE
O23 - Service: lxddCATSCustConnectService - Lexmark International, Inc. - C:\Windows\system32\spool\DRIVERS\W32X86\3\\lxddserv.exe
O23 - Service: lxdd_device - - C:\Windows\system32\lxddcoms.exe
O23 - Service: Performance Service (nTuneService) - NVIDIA - C:\Program Files\NVIDIA Corporation\nTune\nTuneService.exe
O23 - Service: NVIDIA Display Driver Service (nvsvc) - NVIDIA Corporation - C:\Windows\system32\nvvsvc.exe
O23 - Service: LiveShare P2P Server 9 (RoxLiveShare9) - Unknown owner - C:\Program Files\Common Files\Roxio Shared\9.0\SharedCOM\RoxLiveShare9.exe (file missing)
O23 - Service: SBSD Security Center Service (SBSDWSCService) - Safer Networking Ltd. - C:\Program Files\Spybot - Search & Destroy\SDWinSec.exe
O23 - Service: Update Center Service (UpdateCenterService) - NVIDIA - C:\Program Files\NVIDIA Corporation\System Update\UpdateCenterService.exe
O23 - Service: XAudioService - Conexant Systems, Inc. - C:\Windows\system32\DRIVERS\xaudio.exe

--
End of file - 7630 bytes

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Last Post by Heyzaneretro
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I wound up uninstalling and reinstalling several applications; including my antivirus program. That seemed to be the ticket.

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