I suggest you use OpenPOP (as deceptikon mentioned) if you're not interested in learning the mechanics behind POP Mail. You will need to build the services around it for your application.
I would first start with building a one-way WCF service (You call it and it gives you a response). Once you have built that up, it will be easier to teach you how to implement callback contracts for two-way service communication.
Visual Studio has a nice template for a basic WCF service. I suggest you take a look at that and run through some WCF tutorials.
A quick google and This looks like a decent WCF Tutorial to get you started.