Can you please let me now how I can create a connection betwen my application to a Ms Access Database on the server using VPN connection method? I have a database created on a folder on server which is accesible just by VPN connection.

Thanks for your time

Are you saying the VPN connection is not constant?
How often does the application need to connect to the DB through the VPN?
Does it need to connect automatically or can a user initiate the connection?
Is there a possibility you can put the application on the same side of the network as the database?