I am learning to code and I have been working on a game using what I have learned to make it. So I have been making my version of R type C# game and got everything working so far but I run out of ideas how to make this part of the game work.

I wanted to make the boss appear after 5 min of game play and have the smaller opponents disappear. The boss was going to bounce around the screen like a Windows screen saver till the player destroys it (I know how to do that part since I made a pyame do that). The problem is that I can't figure out how to make the boss disappear till the 5min mark and then reappear.

using System;
using System.Collections.Generic;
using System.ComponentModel;
using System.Data;
using System.Drawing;
using System.Linq;
using System.Text;
using System.Threading.Tasks;
using System.Windows.Forms;


namespace game
{
    public partial class Game : Form
    {
        public Game()
        {
            InitializeComponent();
        }
        bool right, left, up, down, space, A;
        //int Plives = 3;//player lives in game
        int score;
        int p = 0;
        int i = 0;
        playerclass pc = new playerclass();
        int miss = 10;//number of missiles

        void start()
        {
            lblgameover.Visible = false;
            powerarmour.Visible = false;
        }


        void Lives()
        {
            if (pc.Plives > 0)
                pc.Plives -=1;
            if (pc.Plives == 3)
            {
                life1.Visible = true;
                life2.Visible = true;
                life3.Visible = true;
            }
            else if (pc.Plives == 2)
            {
                life1.Visible = false;
                life2.Visible = true;
                life3.Visible = true;
            }
            else if (pc.Plives == 1)
            {
                life1.Visible = false;
                life2.Visible = false;
                life3.Visible = true;
            }
            else if (pc.Plives == 0)
            {
                life1.Visible = false;
                life2.Visible = false;
                life3.Visible = false;
            }
        }
        void Health()
        {
            Random hpup = new Random();
            i++;
            int hp;
            healthup.Left -= 8;
            if (i == 100 && healthup.Left < 0)
            {
                hp = hpup.Next(50, 500);
                healthup.Location = new Point(1200, hp);
                // if (healthup.Left < 0)
            }
            if (i == 500)
                i = 0;
        }
        void HitorMiss()
        {
            foreach (Control j in this.Controls)
            {
                foreach (Control i in this.Controls)
                {
                    if (j is PictureBox && j.Tag == "shot" || j is PictureBox && j.Tag == "missile")
                    {
                        if (i is PictureBox && i.Tag == "enemies")
                        {
                            if (j.Bounds.IntersectsWith(i.Bounds))
                            {

                            }

                        }
                    }
                }
            }
            if (Player.Bounds.IntersectsWith(e1.Bounds) || Player.Bounds.IntersectsWith(e1laser.Bounds) || Player.Bounds.IntersectsWith(e2.Bounds) || Player.Bounds.IntersectsWith(e2laser.Bounds) || Player.Bounds.IntersectsWith(e3.Bounds) || Player.Bounds.IntersectsWith(e3laser.Bounds))
            {
                if (healthbar.Value <= 0)
                {
                    Lives();
                }
                if (pc.Plives == 0)
                {
                    timer1.Stop();
                    lblgameover.Visible = true;
                    lblgameover.Text = "Game over";
                    PictureBox bullet = new PictureBox();
                    bullet.SizeMode = PictureBoxSizeMode.AutoSize;
                    bullet.Image = Properties.Resources.Shoot;
                    bullet.BackColor = System.Drawing.Color.Transparent;
                    ((PictureBox)Player).Image = Properties.Resources.explosion;
                }
                else
                    healthbar.Value -= 10;
            }
            if (Player.Bounds.IntersectsWith(healthup.Bounds))
            {
                if (healthbar.Value <= 90)
                {
                    healthbar.Value += 10;
                }
            }
        }

        void BossShoot()
        {
            e4laser.Left -= 50;
            e5laser.Left -= 50;
            if (e4laser.Left < 0 || e4laser.Left < 0)
            {
                e4laser.Left = powerarmour.Left;
                e4laser.Top = powerarmour.Top + 25;
                e5laser.Left = powerarmour.Left;
                e5laser.Top = powerarmour.Top + 60;
            }
        }
        private int _bossTimerIntervalMins => 5;
        void Boss()
        {
            var bossTimer = new System.Timers.Timer();

            bossTimer.Start();
            //
            e4laser.Visible = false;
            e5laser.Visible = false;
            powerarmour.Visible = false;
            //
            bossTimer.Interval = _bossTimerIntervalMins * 60 * 1000;
            bossTimer.Elapsed += timer1_Tick;
            powerarmour.Visible = true;
            e4laser.Visible = true;
            e5laser.Visible = true;

        }

        void Playermovement()
        {
            if (right == true)
            {
                if (Player.Left < 900)
                {
                    Player.Left += 20;
                }
            }
            if (left == true)
            {
                if (Player.Left > 5)
                {
                    Player.Left -= 15;
                }
            }
            if (up == true)
            {
                if (Player.Top > 20)
                {
                    Player.Top -= 20;
                }
            }
            if (down == true)
            {
                if (Player.Top < 550)
                {
                    Player.Top += 20;
                }
            }
        }
        private void Form1_KeyDown(object sender, KeyEventArgs e)
        {
            if (e.KeyCode == Keys.Right)
            {
                right = true;
            }
            if (e.KeyCode == Keys.Left)
            {
                left = true;
            }
            if (e.KeyCode == Keys.Up)
            {
                up = true;
            }
            if (e.KeyCode == Keys.Down)
            {
                down = true;
            }
            if (e.KeyCode == Keys.Space)
            {
                space = true;
                Shot();
            }
            if (e.KeyCode == Keys.A)
            {
                if (nomissiles.Value >= 10)
                {
                    miss--;
                    nomissiles.Value -= 10;
                    A = true;
                    Missile();
                }
            }
        }
        void Missile()
        {
            PictureBox m = new PictureBox();
            m.SizeMode = PictureBoxSizeMode.AutoSize;
            m.Image = Properties.Resources.Missile1;
            m.BackColor = System.Drawing.Color.Transparent;
            m.Tag = "missile";
            m.Left = Player.Left + 100;//moves bullet left or right
            m.Top = Player.Top + 55;//55 is perfect
            this.Controls.Add(m);
            m.BringToFront();
        }
        void movemissile()
        {
            foreach (Control y in this.Controls)
            {
                if (y is PictureBox && y.Tag == "missile")
                {
                    y.Left += 100;//x.Top -= 10;
                    if (y.Top > 900)//<100
                    {
                        this.Controls.Remove(y);
                    }
                }
            }
        }
        private void Form1_KeyUp(object sender, KeyEventArgs e)
        {
            if (e.KeyCode == Keys.Right)
            {
                right = false;
            }
            if (e.KeyCode == Keys.Left)
            {
                left = false;
            }
            if (e.KeyCode == Keys.Up)
            {
                up = false;
            }
            if (e.KeyCode == Keys.Down)
            {
                down = false;
            }
            if (e.KeyCode == Keys.Space)
            {
                space = false;

            }
            if (e.KeyCode == Keys.A)
            {
                A = false;

            }
        }
        void Shot()//positions where players laser shows on the screen
        {
            PictureBox ammo = new PictureBox();
            ammo.SizeMode = PictureBoxSizeMode.AutoSize;
            ammo.Image = Properties.Resources.Shoot;
            ammo.BackColor = System.Drawing.Color.Transparent;
            ammo.Tag = "shot";
            ammo.Left = Player.Left + 100;//moves bullet left or right
            ammo.Top = Player.Top + 55;//55 is perfect
            this.Controls.Add(ammo);
            ammo.BringToFront();
        }
        void MoveShot()
        {
            foreach (Control x in this.Controls)
            {
                if (x is PictureBox && x.Tag == "shot")
                {
                    x.Left += 100;//x.Top -= 10;
                    if (x.Top > 900)//<100
                    {
                        this.Controls.Remove(x);
                    }
                }
            }
            e1laser.Left -= 30;
            if (e1laser.Left < 0)
            {
                e1laser.Left = e1.Left;
                e1laser.Top = e1.Top + 25;
            }
            e2laser.Left -= 30;
            if (e2laser.Left < 0)
            {
                e2laser.Left = e2.Left;
                e2laser.Top = e2.Top + 25;
            }
            e3laser.Left -= 30;
            if (e3laser.Left < 0)
            {
                e3laser.Left = e3.Left;
                e3laser.Top = e3.Top + 25;
            }

        }
        void Enemies_move()
        {
            int a, b, c;
            Random rnd = new Random();
            e1.Left -= 15;
            if (e1.Left < 0)
            {
                a = rnd.Next(30, 560);
                e1.Location = new Point(1200, a);

            }
            //
            e2.Left -= 15;
            if (e2.Left < 0)
            {
                b = rnd.Next(30, 560);
                e2.Location = new Point(1200, b);
            }
            e3.Left -= 15;
            if (e3.Left < 0)
            {
                c = rnd.Next(30, 560);
                e3.Location = new Point(1200, c);
            }
        }
        private void Game_Load(object sender, EventArgs e)
        {

        }
        private void timer1_Tick(object sender, EventArgs e)
        {

            start();
            Boss();
            Health();
            MoveShot();
            Playermovement();
            Enemies_move();
            HitorMiss();
            movemissile();

        }
    }
}

I made some progress on the problem and can make the picturebox disappear till I need it to appear. The problem I have is now the picturebox will flickers for a moment showing the picturebox then disappears. How do I make it just appear?

using System;
using System.Collections.Generic;
using System.ComponentModel;
using System.Data;
using System.Drawing;
using System.Linq;
using System.Text;
using System.Threading.Tasks;
using System.Windows.Forms;
using System.Timers;
using System.Diagnostics;


namespace game
{
    public partial class Game : Form
    {

        System.Timers.Timer timer;
        public Game()
        {
            InitializeComponent();
        }

        bool right, left, up, down, space, A;
        //int Plives = 3;//player lives in game
        int score;
        int p = 0;
        int i = 0;
        int m = 0;
        playerclass pc = new playerclass();
        int miss = 10;//number of missiles

        void start()
        {
            lblgameover.Visible = false;
            powerarmour.Visible = false;
        }


        void Lives()
        {
            if (pc.Plives > 0)
                pc.Plives -=1;
            if (pc.Plives == 3)
            {
                life1.Visible = true;
                life2.Visible = true;
                life3.Visible = true;
            }
            else if (pc.Plives == 2)
            {
                life1.Visible = false;
                life2.Visible = true;
                life3.Visible = true;
            }
            else if (pc.Plives == 1)
            {
                life1.Visible = false;
                life2.Visible = false;
                life3.Visible = true;
            }
            else if (pc.Plives == 0)
            {
                life1.Visible = false;
                life2.Visible = false;
                life3.Visible = false;
            }
        }
        void AddMissiles()
        {
            Random addmiss = new Random();
            m++;
            int mi;
            nmissiles.Left -= 10;
            if(m == 150 && nmissiles.Left < 0)
            {
                mi = addmiss.Next(50, 500);
                nmissiles.Location = new Point(1200, mi);
            }
            if (m == 500)
                m = 0;
        }
        void Health()
        {
            Random hpup = new Random();
            i++;
            int hp;
            healthup.Left -= 8;
            if (i == 100 && healthup.Left < 0)
            {
                hp = hpup.Next(50, 500);
                healthup.Location = new Point(1200, hp);
                // if (healthup.Left < 0)
            }
            if (i == 500)
                i = 0;
        }
        void HitorMiss()
        {
            foreach (Control j in this.Controls)
            {
                foreach (Control i in this.Controls)
                {
                    if (j is PictureBox && j.Tag == "shot" || j is PictureBox && j.Tag == "missile")
                    {
                        if (i is PictureBox && i.Tag == "enemies")
                        {
                            if (j.Bounds.IntersectsWith(i.Bounds))
                            {
                                i.Top = -700;//100;
                                PictureBox bullet = new PictureBox();
                                bullet.SizeMode = PictureBoxSizeMode.AutoSize;
                                bullet.Image = Properties.Resources.Shoot;
                                bullet.BackColor = System.Drawing.Color.Transparent;
                                ((PictureBox)j).Image = Properties.Resources.explosion;
                                score++;
                                lblscore.Text = "" + score;
                            }
                            //animate explosion as enemies blow up after getting hit
                        }
                    }
                }
            }
            if (Player.Bounds.IntersectsWith(e1.Bounds) || Player.Bounds.IntersectsWith(e1laser.Bounds) || Player.Bounds.IntersectsWith(e2.Bounds) || Player.Bounds.IntersectsWith(e2laser.Bounds) || Player.Bounds.IntersectsWith(e3.Bounds) || Player.Bounds.IntersectsWith(e3laser.Bounds))
            {
                if (healthbar.Value <= 0)
                {
                    Lives();
                    //healthbar.Value = 100;
                }
                if (pc.Plives == 0)
                {
                    timer1.Stop();
                    lblgameover.Visible = true;
                    lblgameover.Text = "Game over";
                    PictureBox bullet = new PictureBox();
                    bullet.SizeMode = PictureBoxSizeMode.AutoSize;
                    bullet.Image = Properties.Resources.Shoot;
                    bullet.BackColor = System.Drawing.Color.Transparent;
                    ((PictureBox)Player).Image = Properties.Resources.explosion;
                }
                else
                    healthbar.Value -= 10;
            }
            if (Player.Bounds.IntersectsWith(healthup.Bounds))
            {
                if (healthbar.Value <= 90)
                {
                    healthbar.Value += 10;
                }
            }
            if(Player.Bounds.IntersectsWith(nmissiles.Bounds))
            {
                nomissiles.Value = 100;
            }
        }
        void Playermovement()
        {
            if (right == true)
            {
                if (Player.Left < 900)
                {
                    Player.Left += 20;
                }
            }
            if (left == true)
            {
                if (Player.Left > 5)
                {
                    Player.Left -= 15;
                }
            }
            if (up == true)
            {
                if (Player.Top > 20)
                {
                    Player.Top -= 20;
                }
            }
            if (down == true)
            {
                if (Player.Top < 550)
                {
                    Player.Top += 20;
                }
            }
        }

        private void Form1_KeyDown(object sender, KeyEventArgs e)
        {
            if (e.KeyCode == Keys.Right)
            {
                right = true;
            }
            if (e.KeyCode == Keys.Left)
            {
                left = true;
            }
            if (e.KeyCode == Keys.Up)
            {
                up = true;
            }
            if (e.KeyCode == Keys.Down)
            {
                down = true;
            }
            if (e.KeyCode == Keys.Space)
            {
                space = true;
                Shot();
            }
            if (e.KeyCode == Keys.A)
            {
                if (nomissiles.Value >= 10)
                {
                    miss--;
                    nomissiles.Value -= 10;
                    A = true;
                    Missile();
                }
            }
        }
        void Missile()
        {
            PictureBox m = new PictureBox();
            m.SizeMode = PictureBoxSizeMode.AutoSize;
            m.Image = Properties.Resources.Missile1;
            m.BackColor = System.Drawing.Color.Transparent;
            m.Tag = "missile";
            m.Left = Player.Left + 100;//moves bullet left or right
            m.Top = Player.Top + 55;//55 is perfect
            this.Controls.Add(m);
            m.BringToFront();
        }
        void movemissile()
        {
            foreach (Control y in this.Controls)
            {
                if (y is PictureBox && y.Tag == "missile")
                {
                    y.Left += 100;//x.Top -= 10;
                    if (y.Top > 900)//<100
                    {
                        this.Controls.Remove(y);
                    }
                }
            }
        }
        private void Form1_KeyUp(object sender, KeyEventArgs e)
        {
            if (e.KeyCode == Keys.Right)
            {
                right = false;
            }
            if (e.KeyCode == Keys.Left)
            {
                left = false;
            }
            if (e.KeyCode == Keys.Up)
            {
                up = false;
            }
            if (e.KeyCode == Keys.Down)
            {
                down = false;
            }
            if (e.KeyCode == Keys.Space)
            {
                space = false;
            }
            if (e.KeyCode == Keys.A)
            {
                A = false;
            }
        }
        void Shot()//positions where players laser shows on the screen
        {
            PictureBox ammo = new PictureBox();
            ammo.SizeMode = PictureBoxSizeMode.AutoSize;
            ammo.Image = Properties.Resources.Shoot;
            ammo.BackColor = System.Drawing.Color.Transparent;
            ammo.Tag = "shot";
            ammo.Left = Player.Left + 100;//moves bullet left or right
            ammo.Top = Player.Top + 55;//55 is perfect
            this.Controls.Add(ammo);
            ammo.BringToFront();
        }
        void MoveShot()
        {
            foreach (Control x in this.Controls)
            {
                if (x is PictureBox && x.Tag == "shot")
                {
                    x.Left += 100;//x.Top -= 10;
                    if (x.Top > 900)//<100
                    {
                        this.Controls.Remove(x);
                    }
                }
            }
            e1laser.Left -= 30;
            if (e1laser.Left < 0)
            {
                e1laser.Left = e1.Left;
                e1laser.Top = e1.Top + 25;
            }
            e2laser.Left -= 30;
            if (e2laser.Left < 0)
            {
                e2laser.Left = e2.Left;
                e2laser.Top = e2.Top + 25;
            }
            e3laser.Left -= 30;
            if (e3laser.Left < 0)
            {
                e3laser.Left = e3.Left;
                e3laser.Top = e3.Top + 25;
            }
        }
        void Enemies_move()
        {
            int a, b, c;
            Random rnd = new Random();
            e1.Left -= 15;
            if (e1.Left < 0 )
            {
                a = rnd.Next(30, 560);
                e1.Location = new Point(1200, a);

            }
            //
            e2.Left -= 15;
            if (e2.Left < 0)
            {
                b = rnd.Next(30, 560);
                e2.Location = new Point(1200, b);
            }
            e3.Left -= 15;
            if (e3.Left < 0)
            {
                c = rnd.Next(30, 560);
                e3.Location = new Point(1200, c);
            }
        }
        void Boss()
        {
            powerarmour.Visible = false;
            bosstimer.Interval = 5000;
            bosstimer.Enabled = true;
        }
        private void Game_Load(object sender, EventArgs e)
        {


        }
        private void bosstimer_Tick(object sender, EventArgs e)
        {



                bosstimer.Enabled = true;
                powerarmour.Visible = true;

            }
            private void timer1_Tick(object sender, EventArgs e)
            {

                start();
                Boss();
                Health();
                MoveShot();
                Playermovement();
                Enemies_move();
                HitorMiss();
                movemissile();
                AddMissiles();
                //BossShoot();

            }
        }
    }
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