I would like to know what is the best combination of the following to use for a business application like ERP/CRM, that will be web based?

1) Using extJS + ASP.NET + C#
2) Using Silverlight + C#

Personally I'd use Silverlight. The main advantage for me being, you can implement INotifyPropertyChanged . Drawback can be updating to newer versions, since all browser cache Silverlight locally.

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