I have heard you can efficiently use your GPU to do fast floating point calculations. This can be done using OpenGL but you may have to use the library in an unorthodox way or graphics card toolkits such as CUDA (by nVidia) which I guess is Graphics card specific.

Does anyone have an experience in this and an opinion on the best tools available now.

Thanks!

Indeed CUDA is only for nVidia cards. I suggest better using OpenCL. Also if these calculations is only for computing image transformations- you can try Pixel Shader.

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