My project is almost over,
i have made the installable version as well using the normal deplyment stuff using setup project.
all i want to knw now is tat is it possible to make my installable version as one time installation.
that is once installed wit the client, the setup file shud not work again on some other client....
plz help..

Yes but this is probably a bad idea. You're going to have bugs or some reason to upgrade and you will create a support nightmare for yourself. Add a custom action to the installer on install where it creates a deeply embedded registry key if it doesn't exist, and if it does exist have the installer bomb out (throw an exception).

Serkan is our residential installer guru and i'm sure he will be on the thread shortly.