In my project, I have a page which having,
Ajax PopupExtender,UpdatePanel,<AJX:TabContainer> .

When I set control values(textboxes,labels) on that page,
I am not able to refresh the page even through web browser(retype url).
All values persist on the controls.

Anybody can talk about problem and solution?
Thanks in advance.

try clearing a browser cache !

Thanks for the suggestion, And I have done this using following code.

void ClearBrowserPageCache()