I've got everything ready to go except for genre selection. I have a combo box added to the bottom of the player at the bottom of the program with a list of different genres. My question is, how do I get the radio to load one of the genres when clicked?

The guide that I followed said that I can add a button to change stations and add this line to the button's code to make it change to that station.

player1.URL = "URL Here"

Please keep it simple, I'm still new to VB.Net.

Can you post some of the code that you already have please so that we can help better.
From what you have said I think that you might need to use one of the actions for the combo box of OnValueChanged or something similar...

ParkeyParker